SCOPe 2.06: Domain d5j6aa1: 5j6a A:11-177

Lineage for d5j6aa1 (5j6a A:11-177)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.5: alpha-ketoacid dehydrogenase kinase, N-terminal domain [69012] (2 families)
   automatically mapped to Pfam PF10436

5. Family a.29.5.1: alpha-ketoacid dehydrogenase kinase, N-terminal domain [69013] (3 proteins)

6. Protein automated matches [230549] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [230552] (19 PDB entries)

8. Domain d5j6aa1: 5j6a A:11-177 [329006]
   automated match to d1y8pa1
   complexed with p46

Details for d5j6aa1

PDB Entry: 5j6a, 2.05 Å

PDB Description: crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor ps46

PDB Compounds: (A:) [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial

SCOPe Domain Sequences for d5j6aa1:

Sequence, based on SEQRES records:

>d5j6aa1 a.29.5.1 (A:11-177) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aslagapkyiehfskfspsplsmkqfldfgssnacektsftflrqelpvrlanimkeinl
lpdrvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptm
aqgvleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifd

Sequence, based on observed residues (ATOM records):

>d5j6aa1 a.29.5.1 (A:11-177) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aslagapkyiehfskfspsplsmkqfldfgscektsftflrqelpvrlanimkeinllpd
rvlstpsvqlvqswyvqslldimefldkdpedhrtlsqftdalvtirnrhndvvptmaqg
vleykdtygddpvsnqniqyfldrfylsrisirmlinqhtlifd

Timeline for d5j6aa1:

• d5j6aa1 is new in SCOPe 2.06-stable
  
• d5j6aa1 appears in SCOPe 2.07
  
• d5j6aa1 appears in the current release, SCOPe 2.08