SCOPe 2.08: Domain d5hiab_: 5hia B:

Lineage for d5hiab_ (5hia B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.61: PRTase-like [53270] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.61.1: PRTase-like [53271] (3 families)

5. Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 proteins)

6. Protein Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53284] (20 PDB entries)

8. Domain d5hiab_: 5hia B: [328811]
   automated match to d4raoa_
   complexed with mg, ypg

Details for d5hiab_

PDB Entry: 5hia, 1.77 Å

PDB Description: human hypoxanthine-guanine phosphoribosyltransferase in complex with [3r,4r]-4-guanin-9-yl-3-((s)-2-hydroxy-2-phosphonoethyl)oxy-1-n- (phosphonopropionyl)pyrrolidine

PDB Compounds: (B:) hypoxanthine-guanine phosphoribosyltransferase

SCOPe Domain Sequences for d5hiab_:

Sequence, based on SEQRES records:

>d5hiab_ c.61.1.1 (B:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
rspgvvisddepgydldlfaipnhyaedlervfiphglimdrterlardvmkemgghhiv
alcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikviggddls
tltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfei
pdkfvvgyaldyneyfrdlnhvavisetgkakyka

Sequence, based on observed residues (ATOM records):

>d5hiab_ c.61.1.1 (B:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
rspgvvisddepgydldlfaipnhyaedlervfiphglimdrterlardvmkemgghhiv
alcvlkggykffadlldyikalnrnsdrsipmtvdfirlkkviggddlstltgknvlive
diidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeipdkfvvgyald
yneyfrdlnhvavisetgkakyka

Timeline for d5hiab_:

• d5hiab_ first appeared in SCOPe 2.06
  
• d5hiab_ appears in SCOPe 2.07