SCOPe 2.08: Domain d5b5pa_: 5b5p A:

Lineage for d5b5pa_ (5b5p A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Collagenase-3 (MMP-13) [55540] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55541] (47 PDB entries)

8. Domain d5b5pa_: 5b5p A: [328533]
   automated match to d1euba_
   complexed with ca, wnn, zn

Details for d5b5pa_

PDB Entry: 5b5p, 1.6 Å

PDB Description: crystal structure of the catalytic domain of mmp-13 complexed with 4- oxo-n-(3-(2-(1h-1,2,4-triazol-3-ylsulfanyl)ethoxy)benzyl)-3,4- dihydroquinazoline-2-carboxamide

PDB Compounds: (A:) collagenase 3

SCOPe Domain Sequences for d5b5pa_:

Sequence, based on SEQRES records:

>d5b5pa_ d.92.1.11 (A:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgded

Sequence, based on observed residues (ATOM records):

>d5b5pa_ d.92.1.11 (A:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytghfmlpdddvqgiqslygpgded

Timeline for d5b5pa_:

• d5b5pa_ first appeared in SCOPe 2.06
  
• d5b5pa_ appears in SCOPe 2.07