Lineage for d5l6yc_ (5l6y C:)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2705447Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2705448Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2705548Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. 2705579Protein Interleukin-13 (IL-13) [63532] (1 species)
  7. 2705580Species Human (Homo sapiens) [TaxId:9606] [63533] (13 PDB entries)
  8. 2705585Domain d5l6yc_: 5l6y C: [327425]
    Other proteins in same PDB: d5l6yh_, d5l6yl1, d5l6yl2
    automated match to d5e4ea_
    complexed with fmt

Details for d5l6yc_

PDB Entry: 5l6y (more details), 1.99 Å

PDB Description: il13 in complex with tralokinumab
PDB Compounds: (C:) interleukin-13

SCOPe Domain Sequences for d5l6yc_:

Sequence, based on SEQRES records: (download)

>d5l6yc_ a.26.1.2 (C:) Interleukin-13 (IL-13) {Human (Homo sapiens) [TaxId: 9606]}
ppstalrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsaiektq
rmlsgfcphkvsagqfsslhvrdtkievaqfvkdlllhlkklfregrfn

Sequence, based on observed residues (ATOM records): (download)

>d5l6yc_ a.26.1.2 (C:) Interleukin-13 (IL-13) {Human (Homo sapiens) [TaxId: 9606]}
ppstalrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsaiektq
rmlsgfcdtkievaqfvkdlllhlkklfregrfn

SCOPe Domain Coordinates for d5l6yc_:

Click to download the PDB-style file with coordinates for d5l6yc_.
(The format of our PDB-style files is described here.)

Timeline for d5l6yc_: