SCOPe 2.03: Domain d1d5ra2: 1d5r A:14-187

Lineage for d1d5ra2 (1d5r A:14-187)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.1: Dual specificity phosphatase-like [52800] (9 proteins)

6. Protein Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52819] (1 PDB entry)

8. Domain d1d5ra2: 1d5r A:14-187 [32697]
   Other proteins in same PDB: d1d5ra1
   complexed with tla

Details for d1d5ra2

PDB Entry: 1d5r, 2.1 Å

PDB Description: crystal structure of the pten tumor suppressor

PDB Compounds: (A:) phosphoinositide phosphotase pten

SCOPe Domain Sequences for d1d5ra2:

Sequence; same for both SEQRES and ATOM records:

>d1d5ra2 c.45.1.1 (A:14-187) Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
rryqedgfdldltyiypniiamgfpaerlegvyrnniddvvrfldskhknhykiynlcae
rhydtakfncrvaqypfedhnppqlelikpfcedldqwlseddnhvaaihckagkgrtgv
micayllhrgkflkaqealdfygevrtrdkkgvtipsqrryvyyysyllknhld

Timeline for d1d5ra2:

• d1d5ra2 first appeared (with stable ids) in SCOP 1.55
  
• d1d5ra2 appears in SCOPe 2.02
  
• d1d5ra2 appears in SCOPe 2.04
  
• d1d5ra2 appears in the current release, SCOPe 2.08