SCOP 1.67: Domain d1a5y__: 1a5y -

Lineage for d1a5y__ (1a5y -)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (3 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (5 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein Tyrosine phosphatase [52806] (7 species)

7. Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (58 PDB entries)

8. Domain d1a5y__: 1a5y - [32673]
   cysteinyl-phosphate intermediate

Details for d1a5y__

PDB Entry: 1a5y, 2.5 Å

PDB Description: protein tyrosine phosphatase 1b cysteinyl-phosphate intermediate

SCOP Domain Sequences for d1a5y__:

Sequence; same for both SEQRES and ATOM records:

>d1a5y__ c.45.1.2 (-) Tyrosine phosphatase {Human (Homo sapiens), 1B}
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdp
ssvdikkvlldmrkfrmgliataeqlrfsylaviegakfimgds

Timeline for d1a5y__:

• d1a5y__ first appeared (with stable ids) in SCOP 1.55
  
• d1a5y__ appears in SCOP 1.65
  
• d1a5y__ appears in SCOP 1.69
  
• d1a5y__ appears in the current release, SCOPe 2.08, called d1a5ya_