Lineage for d1gfya_ (1gfy A:)

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 395608Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 395609Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (3 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 395648Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (5 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 395674Protein Tyrosine phosphatase [52806] (7 species)
  7. 395675Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (58 PDB entries)
  8. 395699Domain d1gfya_: 1gfy A: [32666]
    complexed with col; mutant

Details for d1gfya_

PDB Entry: 1gfy (more details), 2.13 Å

PDB Description: residue 259 is a key determinant of substrate specificity of protein- tyrosine phosphatase 1b and alpha

SCOP Domain Sequences for d1gfya_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1gfya_ c.45.1.2 (A:) Tyrosine phosphatase {Human (Homo sapiens), 1B}
mekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryvnvspfdhsriklhqe
dndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkca
qywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwpdf
gvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdps
svdikkvlldmrkfrcqliqtadqlrfsylaviegakfimgdssvqdqwkelshed

SCOP Domain Coordinates for d1gfya_:

Click to download the PDB-style file with coordinates for d1gfya_.
(The format of our PDB-style files is described here.)

Timeline for d1gfya_: