SCOP 1.67: Domain d1aax__: 1aax -

Lineage for d1aax__ (1aax -)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (3 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (5 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein Tyrosine phosphatase [52806] (7 species)

7. Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (58 PDB entries)

8. Domain d1aax__: 1aax - [32657]
   complexed with bpm, mo6; mutant

Details for d1aax__

PDB Entry: 1aax, 1.9 Å

PDB Description: crystal structure of protein tyrosine phosphatase 1b complexed with two bis(para-phosphophenyl)methane (bppm) molecules

SCOP Domain Sequences for d1aax__:

Sequence; same for both SEQRES and ATOM records:

>d1aax__ c.45.1.2 (-) Tyrosine phosphatase {Human (Homo sapiens), 1B}
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhssagigrsgtfcladtclllmdkrkdp
ssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshed

Timeline for d1aax__:

• d1aax__ first appeared (with stable ids) in SCOP 1.55
  
• d1aax__ appears in SCOP 1.65
  
• d1aax__ appears in SCOP 1.69
  
• d1aax__ appears in the current release, SCOPe 2.08, called d1aaxa_