SCOPe 2.08: Domain d5hnix_: 5hni X:

Lineage for d5hnix_ (5hni X:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Hepatocyte growth factor receptor, c-MET [103300] (1 species)
   PTK group; HGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [103301] (67 PDB entries)

8. Domain d5hnix_: 5hni X: [326491]
   automated match to d1r0pa_
   complexed with 63b

Details for d5hnix_

PDB Entry: 5hni, 1.71 Å

PDB Description: crystal structure of cmet wt with compound 3

PDB Compounds: (X:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d5hnix_:

Sequence, based on SEQRES records:

>d5hnix_ d.144.1.7 (X:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
vqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnritdigevs
qfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdli
gfglqvakgmkflaskkfvhrdlaarncmldekftvkvadfglardmydkefdsvhnktg
aklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrl
lqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyvhvnaty

Sequence, based on observed residues (ATOM records):

>d5hnix_ d.144.1.7 (X:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
vqavqhvvigpgcvyhgtlkihcavksvsqfltegiimkdfshpnvlsllgiclrsegsp
lvvlpymkhgdlrnfirnethnptvkdligfglqvakgmkflaskkfvhrdlaarncmld
ekftvkvadfglardmywmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfd
itvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyvh
vnaty

Timeline for d5hnix_:

• d5hnix_ first appeared in SCOPe 2.06
  
• d5hnix_ appears in SCOPe 2.07