SCOPe 2.08: Domain d5k8la1: 5k8l A:173-481

Lineage for d5k8la1 (5k8l A:173-481)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (7 proteins)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein automated matches [226986] (8 species)
   not a true protein

7. Species Zika virus [TaxId:64320] [317808] (28 PDB entries)

8. Domain d5k8la1: 5k8l A:173-481 [325022]
   Other proteins in same PDB: d5k8la2
   automated match to d2bhra2
   complexed with cl, edo, gsp, mpd

Details for d5k8la1

PDB Entry: 5k8l, 1.75 Å

PDB Description: crystal structure of zikv ns3 helicase in complex with gtp-gammar s

PDB Compounds: (A:) ZIKV NS3 helicase

SCOPe Domain Sequences for d5k8la1:

Sequence, based on SEQRES records:

>d5k8la1 c.37.1.14 (A:173-481) automated matches {Zika virus [TaxId: 64320]}
etpvecfepsmlkkkqltvldlhpgagktrrvlpeivreaiktrlrtvilaptrvvaaem
eealrglpvrymttavnvthsgteivdlmchatftsrllqpirvpnynlyimdeahftdp
ssiaargyistrvemgeaaaifmtatppgtrdafpdsnspimdtevevperawssgfdwv
tdhsgktvwfvpsvrngneiaacltkagkrviqlsrktfetefqktkhqewdfvvttdis
emganfkadrvidsrrclkpvildgervilagpmpvthasaaqrrgrigrnpnkpgdeyl
ygggcaetd

Sequence, based on observed residues (ATOM records):

>d5k8la1 c.37.1.14 (A:173-481) automated matches {Zika virus [TaxId: 64320]}
etpvecfepsmlkkkqltvldlhpgagktrrvlpeivreaiktrlrtvilaptrvvaaem
eealrglpvrymttavnvteivdlmchatftsrllqpirvpnynlyimdeahftdpssia
argyistrvemgeaaaifmtatppgtrdafpdsnspimdtevevperawssgfdwvtdhs
gktvwfvpsvrngneiaacltkagkrviqlsrktfetefqktkhqewdfvvttdisemga
nfkadrvidsrrclkpvildgervilagpmpvthasaaqrrgrigrnpnkpgdeylyggg
caetd

Timeline for d5k8la1:

• d5k8la1 first appeared in SCOPe 2.06
  
• d5k8la1 appears in SCOPe 2.07