SCOPe 2.08: Domain d5gpga1: 5gpg A:109-224

Lineage for d5gpga1 (5gpg A:109-224)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.26: FKBP-like [54533] (3 superfamilies)
   core: beta(2)-alpha-beta(2); antiparallel beta-sheet

4. Superfamily d.26.1: FKBP-like [54534] (4 families)

5. Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 proteins)

6. Protein FKBP25 [54543] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [54544] (3 PDB entries)

8. Domain d5gpga1: 5gpg A:109-224 [324038]
   Other proteins in same PDB: d5gpga2, d5gpgb1, d5gpgb2
   automated match to d1pbka_
   complexed with rap

Details for d5gpga1

PDB Entry: 5gpg, 1.67 Å

PDB Description: co-crystal structure of the fk506 binding domain of human fkbp25, rapamycin and the frb domain of human mtor

PDB Compounds: (A:) Peptidyl-prolyl cis-trans isomerase FKBP3

SCOPe Domain Sequences for d5gpga1:

Sequence, based on SEQRES records:

>d5gpga1 d.26.1.1 (A:109-224) FKBP25 {Human (Homo sapiens) [TaxId: 9606]}
pkytksvlkkgdktnfpkkgdvvhcwytgtlqdgtvfdtniqtsakkkknakplsfkvgv
gkvirgwdealltmskgekarleiepewaygkkgqpdakippnakltfevelvdid

Sequence, based on observed residues (ATOM records):

>d5gpga1 d.26.1.1 (A:109-224) FKBP25 {Human (Homo sapiens) [TaxId: 9606]}
pkytksvlkkgdktnfpkkgdvvhcwytgtlqdgtvfdtniqnakplsfkvgvgkvirgw
dealltmskgekarleiepewaygkkgqpdakippnakltfevelvdid

Timeline for d5gpga1:

• d5gpga1 first appeared in SCOPe 2.06
  
• d5gpga1 appears in SCOPe 2.07