SCOPe 2.08: Domain d5gpgb1: 5gpg B:2021-2112

Lineage for d5gpgb1 (5gpg B:2021-2112)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (29 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family)
   automatically mapped to Pfam PF08771

5. Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 proteins)

6. Protein automated matches [193175] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [193176] (5 PDB entries)

8. Domain d5gpgb1: 5gpg B:2021-2112 [323893]
   Other proteins in same PDB: d5gpga1, d5gpga2, d5gpgb2
   automated match to d2gaqa_
   complexed with rap

Details for d5gpgb1

PDB Entry: 5gpg, 1.67 Å

PDB Description: co-crystal structure of the fk506 binding domain of human fkbp25, rapamycin and the frb domain of human mtor

PDB Compounds: (B:) Serine/threonine-protein kinase mTOR

SCOPe Domain Sequences for d5gpgb1:

Sequence; same for both SEQRES and ATOM records:

>d5gpgb1 a.24.7.1 (B:2021-2112) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ilwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlme
aqewcrkymksgnvkdltqawdlyyhvfrris

Timeline for d5gpgb1:

• d5gpgb1 first appeared in SCOPe 2.06
  
• d5gpgb1 appears in SCOPe 2.07