Lineage for d5kyab1 (5kya B:297-528)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2335122Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2335123Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2335124Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2336144Protein automated matches [190059] (14 species)
    not a true protein
  7. 2336166Species Human (Homo sapiens) [TaxId:9606] [187214] (157 PDB entries)
  8. 2336395Domain d5kyab1: 5kya B:297-528 [323105]
    Other proteins in same PDB: d5kyaa2, d5kyab2, d5kyae2, d5kyaf2
    automated match to d4j5xc_
    complexed with 6y4

Details for d5kyab1

PDB Entry: 5kya (more details), 2.6 Å

PDB Description: brain penetrant liver x receptor (lxr) modulators based on a 2,4,5,6- tetrahydropyrrolo[3,4-c]pyrazole core
PDB Compounds: (B:) Retinoic acid receptor RXR-beta

SCOPe Domain Sequences for d5kyab1:

Sequence, based on SEQRES records: (download)

>d5kyab1 a.123.1.1 (B:297-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eempvdrileaelaveqksdqgvegpggtggsgsspndpvtnicqaadkqlftlvewakr
iphfsslplddqvillragwnelliasfshrsidvrdgillatglhvhrnsahsagvgai
fdrvltelvskmrdmrmdktelgclraiilfnpdakglsnpsevevlrekvyasletyck
qkypeqqgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemlea

Sequence, based on observed residues (ATOM records): (download)

>d5kyab1 a.123.1.1 (B:297-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eempvdrileaelavepvtnicqaadkqlftlvewakriphfsslplddqvillragwne
lliasfshrsidvrdgillatglhvhrnsahsagvgaifdrvltelvskmrdmrmdktel
gclraiilfnpdakglsnpsevevlrekvyasletyckqkypeqqgrfaklllrlpalrs
iglkclehlfffkligdtflmemlea

SCOPe Domain Coordinates for d5kyab1:

Click to download the PDB-style file with coordinates for d5kyab1.
(The format of our PDB-style files is described here.)

Timeline for d5kyab1: