Lineage for d5ixyb2 (5ixy B:160-331)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2556795Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 2556796Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 2556797Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 2556804Protein Lactate dehydrogenase [56339] (20 species)
  7. 2556875Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (36 PDB entries)
  8. 2556941Domain d5ixyb2: 5ixy B:160-331 [322673]
    Other proteins in same PDB: d5ixya1, d5ixyb1, d5ixyc1, d5ixyd1
    automated match to d4jnka2
    complexed with gn2, nad, so4

Details for d5ixyb2

PDB Entry: 5ixy (more details), 3 Å

PDB Description: lactate dehydrogenase in complex with hydroxylactam inhibitor compound 31: (2~{s})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4- oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one
PDB Compounds: (B:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d5ixyb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5ixyb2 d.162.1.1 (B:160-331) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d5ixyb2:

Click to download the PDB-style file with coordinates for d5ixyb2.
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Timeline for d5ixyb2: