SCOPe 2.08: Domain d5k0bd1: 5k0b D:3-218

Lineage for d5k0bd1 (5k0b D:3-218)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.1: COMT-like [53336] (4 proteins)

6. Protein Catechol O-methyltransferase, COMT [53337] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [53338] (87 PDB entries)

8. Domain d5k0bd1: 5k0b D:3-218 [322298]
   Other proteins in same PDB: d5k0bd2
   automated match to d3u81a_
   complexed with 6ps, cl, cxs, edo, k, po4

Details for d5k0bd1

PDB Entry: 5k0b, 2.36 Å

PDB Description: crystal structure of comt in complex with 2,4-dimethyl-5-[3-(1- phenylethyl)-1h-pyrazol-5-yl]-1,3-thiazole

PDB Compounds: (D:) Catechol O-methyltransferase

SCOPe Domain Sequences for d5k0bd1:

Sequence; same for both SEQRES and ATOM records:

>d5k0bd1 c.66.1.1 (D:3-218) Catechol O-methyltransferase, COMT {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspslv
lelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqdl
ipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvlladnvivpgtpdflay
vrgsssfecthyssyleymkvvdglekaiyqgpssp

Timeline for d5k0bd1:

• d5k0bd1 first appeared in SCOPe 2.06
  
• d5k0bd1 appears in SCOPe 2.07