SCOPe 2.08: Domain d5egaa_: 5ega A:

Lineage for d5egaa_ (5ega A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.34: PA N-terminal domain [254166] (3 proteins)
   Pfam PF00603; relationship to endonucleases discussed in PubMed 19194458

6. Protein PA N-terminal domain [254375] (8 species)

7. Species Influenza A virus [TaxId:93838] [254808] (91 PDB entries)

8. Domain d5egaa_: 5ega A: [321906]
   automated match to d4e5ed_
   complexed with gk0, mn

Details for d5egaa_

PDB Entry: 5ega, 2.15 Å

PDB Description: 2009 h1n1 pa endonuclease domain in complex with an n-acylhydrazone inhibitor

PDB Compounds: (A:) Polymerase acidic protein

SCOPe Domain Sequences for d5egaa_:

Sequence; same for both SEQRES and ATOM records:

>d5egaa_ c.52.1.34 (A:) PA N-terminal domain {Influenza A virus [TaxId: 93838]}
medfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdggskhrfeii
egrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankik
sekthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqser

Timeline for d5egaa_:

• d5egaa_ first appeared in SCOPe 2.06
  
• d5egaa_ appears in SCOPe 2.07