SCOPe 2.05: Domain d1f5na2: 1f5n A:7-283

Lineage for d1f5na2 (1f5n A:7-283)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain [52639] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52640] (2 PDB entries)

8. Domain d1f5na2: 1f5n A:7-283 [32152]
   Other proteins in same PDB: d1f5na1
   complexed with gnp, mg

Details for d1f5na2

PDB Entry: 1f5n, 1.7 Å

PDB Description: human guanylate binding protein-1 in complex with the gtp analogue, gmppnp.

PDB Compounds: (A:) interferon-induced guanylate-binding protein 1

SCOPe Domain Sequences for d1f5na2:

Sequence, based on SEQRES records:

>d1f5na2 c.37.1.8 (A:7-283) Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
mtgpmclientngrlmanpealkilsaitqpmvvvaivglyrtgksylmnklagkkkgfs
lgstvqshtkgiwmwcvphpkkpghilvlldteglgdvekgdnqndswifalavllsstf
vynsigtinqqamdqlyyvtelthrirsksspdenenevedsadfvsffpdfvwtlrdfs
ldleadgqpltpdeyltyslklkkgtsqkdetfnlprlcirkffpkkkcfvfdrpvhrrk
laqleklqdeeldpefvqqvadfcsyifsnsktktls

Sequence, based on observed residues (ATOM records):

>d1f5na2 c.37.1.8 (A:7-283) Interferon-induced guanylate-binding protein 1 (GBP1), N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
mtgpmclientngrlmanpealkilsaitqpmvvvaivglyrtgksylmnklagkkkgfs
lgstvqshtkgiwmwcvphpkkpghilvlldteglgdvekgdnqndswifalavllsstf
vynsigtinqqamdqlyyvtelthrirskssvedsadfvsffpdfvwtlrdfsldleadg
qpltpdeyltyslklkkgtsqkdetfnlprlcirkffpkkkcfvfdrpvhrrklaqlekl
qdeeldpefvqqvadfcsyifsnsktktls

Timeline for d1f5na2:

• d1f5na2 first appeared (with stable ids) in SCOP 1.55
  
• d1f5na2 appears in SCOPe 2.04
  
• d1f5na2 appears in SCOPe 2.06
  
• d1f5na2 appears in the current release, SCOPe 2.08