Lineage for d5in4d1 (5in4 D:23-372)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2449371Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2449372Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2449736Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2450794Protein GDP-mannose 4,6-dehydratase [51759] (4 species)
  7. 2450797Species Human (Homo sapiens) [TaxId:9606] [102135] (7 PDB entries)
  8. 2450809Domain d5in4d1: 5in4 D:23-372 [321315]
    Other proteins in same PDB: d5in4a2, d5in4b2, d5in4c2, d5in4d2
    automated match to d1t2aa_
    complexed with 6ck, gdp, nap

Details for d5in4d1

PDB Entry: 5in4 (more details), 1.6 Å

PDB Description: crystal structure of gdp-mannose 4,6 dehydratase bound to a gdp-fucose based inhibitor
PDB Compounds: (D:) GDP-mannose 4,6 dehydratase

SCOPe Domain Sequences for d5in4d1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5in4d1 c.2.1.2 (D:23-372) GDP-mannose 4,6-dehydratase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5in4d1:

Click to download the PDB-style file with coordinates for d5in4d1.
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Timeline for d5in4d1: