SCOPe 2.05: Domain d1gfia2: 1gfi A:33-60,A:182-345

Lineage for d1gfia2 (1gfi A:33-60,A:182-345)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Transducin (alpha subunit) [52623] (4 species)
   common fold is interrupted with an all-alpha domain

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [52625] (21 PDB entries)
   Uniprot P10824

8. Domain d1gfia2: 1gfi A:33-60,A:182-345 [32102]
   Other proteins in same PDB: d1gfia1
   complexed with alf, gdp, mg

Details for d1gfia2

PDB Entry: 1gfi, 2.2 Å

PDB Description: structures of active conformations of gi alpha 1 and the mechanism of gtp hydrolysis

PDB Compounds: (A:) guanine nucleotide-binding protein g

SCOPe Domain Sequences for d1gfia2:

Sequence; same for both SEQRES and ATOM records:

>d1gfia2 c.37.1.8 (A:33-60,A:182-345) Transducin (alpha subunit) {Norway rat (Rattus norvegicus) [TaxId: 10116]}
evkllllgagesgkstivkqmkiiheagXtgivethftfkdlhfkmfdvggqrserkkwi
hcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkkd
lfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcatdtknv
qfvfdavtdviik

Timeline for d1gfia2:

• d1gfia2 first appeared (with stable ids) in SCOP 1.55, called d1gfi_2
  
• d1gfia2 appears in SCOPe 2.04
  
• d1gfia2 appears in SCOPe 2.06
  
• d1gfia2 appears in the current release, SCOPe 2.08