SCOP 1.65: Domain d1gfi_2: 1gfi 33-60,182-345

Lineage for d1gfi_2 (1gfi 33-60,182-345)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (35 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Transducin (alpha subunit) [52623] (2 species)
   common fold is interrupted with an all-alpha domain

7. Species Rat (Rattus norvegicus) [TaxId:10116] [52625] (18 PDB entries)

8. Domain d1gfi_2: 1gfi 33-60,182-345 [32102]
   Other proteins in same PDB: d1gfi_1
   complexed with alf, gdp, mg

Details for d1gfi_2

PDB Entry: 1gfi, 2.2 Å

PDB Description: structures of active conformations of gi alpha 1 and the mechanism of gtp hydrolysis

SCOP Domain Sequences for d1gfi_2:

Sequence; same for both SEQRES and ATOM records:

>d1gfi_2 c.37.1.8 (33-60,182-345) Transducin (alpha subunit) {Rat (Rattus norvegicus)}
evkllllgagesgkstivkqmkiiheagXtgivethftfkdlhfkmfdvggqrserkkwi
hcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkkd
lfeekikksplticypeyagsntyeeaaayiqcqfedlnkrkdtkeiythftcatdtknv
qfvfdavtdviik

Timeline for d1gfi_2:

• d1gfi_2 first appeared (with stable ids) in SCOP 1.55
  
• d1gfi_2 appears in SCOP 1.63
  
• d1gfi_2 appears in SCOP 1.67
  
• d1gfi_2 appears in the current release, SCOPe 2.08, called d1gfia2