SCOP 1.71: Domain d1tx4b_: 1tx4 B:

Lineage for d1tx4b_ (1tx4 B:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (23 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (45 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein RhoA [52612] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52613] (12 PDB entries)

8. Domain d1tx4b_: 1tx4 B: [32045]
   Other proteins in same PDB: d1tx4a_
   complexed with alf, gdp, mg

Details for d1tx4b_

PDB Entry: 1tx4, 1.65 Å

PDB Description: rho/rhogap/gdp(dot)alf4 complex

SCOP Domain Sequences for d1tx4b_:

Sequence, based on SEQRES records:

>d1tx4b_ c.37.1.8 (B:) RhoA {Human (Homo sapiens)}
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgaqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

Sequence, based on observed residues (ATOM records):

>d1tx4b_ c.37.1.8 (B:) RhoA {Human (Homo sapiens)}
airkklvivgdgacgktcllivnskdqfyvptvfenyvadievdgkqvelalwdtagqed
ydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrnde
htrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

Timeline for d1tx4b_:

• d1tx4b_ first appeared (with stable ids) in SCOP 1.55
  
• d1tx4b_ appears in SCOP 1.69
  
• d1tx4b_ appears in SCOP 1.73
  
• d1tx4b_ appears in the current release, SCOPe 2.08