Lineage for d1tx4b_ (1tx4 B:)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families) (S)
    division into families based on beta-sheet topologies
  5. Family c.37.1.8: G proteins [52592] (81 proteins)
    core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest
  6. Protein RhoA [52612] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [52613] (39 PDB entries)
    Uniprot P61586 2-181
  8. Domain d1tx4b_: 1tx4 B: [32045]
    Other proteins in same PDB: d1tx4a_
    complexed with alf, gdp, mg

Details for d1tx4b_

PDB Entry: 1tx4 (more details), 1.65 Å

PDB Description: rho/rhogap/gdp(dot)alf4 complex
PDB Compounds: (B:) transforming protein rhoa

SCOPe Domain Sequences for d1tx4b_:

Sequence, based on SEQRES records: (download)

>d1tx4b_ c.37.1.8 (B:) RhoA {Human (Homo sapiens) [TaxId: 9606]}
airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

Sequence, based on observed residues (ATOM records): (download)

>d1tx4b_ c.37.1.8 (B:) RhoA {Human (Homo sapiens) [TaxId: 9606]}
airkklvivgdgacgktcllivnskdqfyvptvfenyvadievdgkqvelalwdtagqed
ydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrnde
htrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraal

SCOPe Domain Coordinates for d1tx4b_ are not available.

Timeline for d1tx4b_:

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Domains from other chains:
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d1tx4a_