SCOPe 2.07: Domain d5hq3b_: 5hq3 B:

Lineage for d5hq3b_ (5hq3 B:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53480] (16 PDB entries)

8. Domain d5hq3b_: 5hq3 B: [320086]
   automated match to d1maac_
   complexed with mes, vx

Details for d5hq3b_

PDB Entry: 5hq3, 2.6 Å

PDB Description: stable, high-expression variant of human acetylcholinesterase

PDB Compounds: (B:) acetylcholinesterase

SCOPe Domain Sequences for d5hq3b_:

Sequence, based on SEQRES records:

>d5hq3b_ c.69.1.1 (B:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
aellvttrggrlrgirlttpggpvsaflgipfaeppvgprrfrppepkqpwsgvwdattf
qnvcyqyvdtlypgfegtemwnpnrnlsedclylnvwtpyprpknpapvmvwiygggfys
gsssldvydgrflvrtervvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvqe
niaafggdptsvtlfgesagaasvgmhllsppsrglfhrailqsgapnapwayvsreear
rralqlaklvgcppggtggndtelvaclrnrppqelvnhewhvlpqesvfrfsfvpvvdg
dflpdtpealinngdfkgldvlvgvnkdegsyflvygapgfskdneslisreeflegvrv
gvpqvsdlaaeaivlhytdwlhpedpaknrdalsdvvgdhnvicpvaqfaqryaangarv
yayvfehrsstlpwpewmgvphgyeiefifgipldpsrnytkeekifarrlmrywanfar
tgdpneprdpkapqwppytadeqkyvsldlrplevrrglraqacafwnrflpkllsat

Sequence, based on observed residues (ATOM records):

>d5hq3b_ c.69.1.1 (B:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
aellvttrggrlrgirlttpggpvsaflgipfaeppvgprrfrppepkqpwsgvwdattf
qnvcyqyvdtlypgfegtemwnpnrnlsedclylnvwtpyprpknpapvmvwiygggfys
gsssldvydgrflvrtervvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvqe
niaafggdptsvtlfgesagaasvgmhllsppsrglfhrailqsgapnapwayvsreear
rralqlaklvgcppndtelvaclrnrppqelvnhewhvlpqesvfrfsfvpvvdgdflpd
tpealinngdfkgldvlvgvnkdegsyflvygapgfskdneslisreeflegvrvgvpqv
sdlaaeaivlhytdwlhpedpaknrdalsdvvgdhnvicpvaqfaqryaangarvyayvf
ehrsstlpwpewmgvphgyeiefifgipldpsrnytkeekifarrlmrywanfartgdpn
eppqwppytadeqkyvsldlrplevrrglraqacafwnrflpkllsat

Timeline for d5hq3b_:

• d5hq3b_ first appeared in SCOPe 2.06
  
• d5hq3b_ appears in the current release, SCOPe 2.08