SCOPe 2.06: Domain d5cshb_: 5csh B:

Lineage for d5cshb_ (5csh B:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (91 PDB entries)

8. Domain d5cshb_: 5csh B: [319902]
   automated match to d3wara_
   complexed with 54e, act, atp

Details for d5cshb_

PDB Entry: 5csh, 1.59 Å

PDB Description: crystal structure of ck2alpha with compound 4 bound

PDB Compounds: (B:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d5cshb_:

Sequence, based on SEQRES records:

>d5cshb_ d.144.1.7 (B:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpseywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvv

Sequence, based on observed residues (ATOM records):

>d5cshb_ d.144.1.7 (B:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpseywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
qtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaefyhpg
qeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydqlvri
akvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfldkll
rydhqsrltareamehpyfytvv

Timeline for d5cshb_:

• d5cshb_ is new in SCOPe 2.06-stable
  
• d5cshb_ appears in SCOPe 2.07
  
• d5cshb_ appears in the current release, SCOPe 2.08