Lineage for d5dt0a_ (5dt0 A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2218253Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
    OPK group; AIRK subfamily; serine/threonine kinase
  7. 2218254Species Human (Homo sapiens) [TaxId:9606] [90039] (62 PDB entries)
  8. 2218284Domain d5dt0a_: 5dt0 A: [319860]
    automated match to d3h10a_
    complexed with ske

Details for d5dt0a_

PDB Entry: 5dt0 (more details), 2.15 Å

PDB Description: aurora a kinase in complex with jnj-7706621 in space group p6122
PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d5dt0a_:

Sequence, based on SEQRES records: (download)

>d5dt0a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrratlcgtldylppemiegrmh
dekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkh
npsqrpmlrevlehpwitansskp

Sequence, based on observed residues (ATOM records): (download)

>d5dt0a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapsscgtldylppemiegrmhdekvd
lwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqr
pmlrevlehpwitansskp

SCOPe Domain Coordinates for d5dt0a_:

Click to download the PDB-style file with coordinates for d5dt0a_.
(The format of our PDB-style files is described here.)

Timeline for d5dt0a_: