SCOPe 2.01: Domain d6q21d_: 6q21 D:

Lineage for d6q21d_ (6q21 D:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein cH-p21 Ras protein [52593] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52594] (84 PDB entries)
   Uniprot Q6P716

8. Domain d6q21d_: 6q21 D: [31982]
   complexed with gcp, mg

Details for d6q21d_

PDB Entry: 6q21, 1.95 Å

PDB Description: molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

PDB Compounds: (D:) c-h-ras p21 protein catalytic domain

SCOPe Domain Sequences for d6q21d_:

Sequence; same for both SEQRES and ATOM records:

>d6q21d_ c.37.1.8 (D:) cH-p21 Ras protein {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqhklrkl

Timeline for d6q21d_:

• d6q21d_ first appeared (with stable ids) in SCOP 1.55
  
• d6q21d_ appears in SCOP 1.75
  
• d6q21d_ appears in SCOPe 2.02
  
• d6q21d_ appears in the current release, SCOPe 2.08