SCOPe 2.08: Domain d1esmd_: 1esm D:

Lineage for d1esmd_ (1esm D:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.6: Phosphoribulokinase/pantothenate kinase [52584] (6 proteins)

6. Protein Pantothenate kinase PanK [52587] (1 species)
   has a circularly permuted fold compared to the phosphoribulokinase fold

7. Species Escherichia coli [TaxId:562] [52588] (3 PDB entries)
   Uniprot P15044

8. Domain d1esmd_: 1esm D: [31956]
   complexed with coa

Details for d1esmd_

PDB Entry: 1esm, 2.5 Å

PDB Description: structural basis for the feedback regulation of escherichia coli pantothenate kinase by coenzyme a

PDB Compounds: (D:) pantothenate kinase

SCOPe Domain Sequences for d1esmd_:

Sequence, based on SEQRES records:

>d1esmd_ c.37.1.6 (D:) Pantothenate kinase PanK {Escherichia coli [TaxId: 562]}
lmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsrllnfyis
snlrrqavleqflgtngqripyiisiagsvavgksttarvlqallsrwpehrrvelittd
gflhpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliydvipdgd
ktvvqpdilileglnvlqsgmdyphdphhvfvsdfvdfsiyvdapedllqtwyinrflkf
regaftdpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasliltksanh
aveevrlrk

Sequence, based on observed residues (ATOM records):

>d1esmd_ c.37.1.6 (D:) Pantothenate kinase PanK {Escherichia coli [TaxId: 562]}
lmtpylqfdrnqwaalrdsvpmtlsedeiarlkginedlsleevaeiylplsrllnfyis
snlrrqavleqflgtripyiisiagsvavgksttarvlqallsrwpehrrvelittdgfl
hpnqvlkerglmkkkgfpesydmhrlvkfvsdlksgvpnvtapvyshliydvipdgdktv
vqpdilileglnvlqsgmdyphhvfvsdfvdfsiyvdapedllqtwyinrflkfregaft
dpdsyfhnyakltkeeaiktamtlwkeinwlnlkqnilptrerasliltksanhaveevr
lrk

Timeline for d1esmd_:

• d1esmd_ first appeared (with stable ids) in SCOP 1.55
  
• d1esmd_ appears in SCOPe 2.07