SCOP 1.65: Domain d4tmka_: 4tmk A:

Lineage for d4tmka_ (4tmk A:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (16 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (4 species)

7. Species Escherichia coli [TaxId:562] [52565] (2 PDB entries)

8. Domain d4tmka_: 4tmk A: [31930]
   complexed with t5a

Details for d4tmka_

PDB Entry: 4tmk, 1.98 Å

PDB Description: complex of e. coli thymidylate kinase with the bisubstrate inhibitor tp5a

SCOP Domain Sequences for d4tmka_:

Sequence; same for both SEQRES and ATOM records:

>d4tmka_ c.37.1.1 (A:) Thymidylate kinase {Escherichia coli}
rskyivieglegagkttarnvvvetleqlgirdmvftrepggtqlaeklrsllldiksvg
devitdkaevlmfyaarvqlvetvikpalangtwvigdrhdlstqayqgggrgidqhmla
tlrdavlgdfrpdltlyldvtpevglkrarargeldrieqesfdffnrtrarylelaaqd
ksihtidatqpleavmdairttvthwvkel

Timeline for d4tmka_:

• d4tmka_ first appeared (with stable ids) in SCOP 1.55
  
• d4tmka_ appears in SCOP 1.63
  
• d4tmka_ appears in SCOP 1.67
  
• d4tmka_ appears in the current release, SCOPe 2.08