SCOPe 2.01: Domain d2tmkb_: 2tmk B:

Lineage for d2tmkb_ (2tmk B:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidylate kinase [52563] (4 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)

8. Domain d2tmkb_: 2tmk B: [31929]
   complexed with atm, so4

Details for d2tmkb_

PDB Entry: 2tmk, 2.4 Å

PDB Description: yeast thymidylate kinase complexed with 3'-azido-3'-deoxythymidine monophosphate (azt-mp)

PDB Compounds: (B:) thymidylate kinase

SCOPe Domain Sequences for d2tmkb_:

Sequence, based on SEQRES records:

>d2tmkb_ c.37.1.1 (B:) Thymidylate kinase {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
grgkliliegldrtgkttqcnilykklqpnckllkfperstrigglineyltddsfqlsd
qaihllfsanrweivdkikkdllegknivmdryvysgvaysaakgtngmdldwclqpdvg
llkpdltlflstqdvdnnaeksgfgderyetvkfqekvkqtfmklldkeirkgdesitiv
dvtnkgiqevealiwqivepvlsthidhdkfsff

Sequence, based on observed residues (ATOM records):

>d2tmkb_ c.37.1.1 (B:) Thymidylate kinase {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
grgkliliegldrtgkttqcnilykklqpnckllkfperstrigglineyltddsfqlsd
qaihllfsanrweivdkikkdllegknivmdryvysgvaysaakgtngmdldwclqpdvg
llkpdltlflstqfgderyetvkfqekvkqtfmklldkeirkgdesitivdvtnkgiqev
ealiwqivepvlsthidhdkfsff

Timeline for d2tmkb_:

• d2tmkb_ first appeared (with stable ids) in SCOP 1.55
  
• d2tmkb_ appears in SCOP 1.75
  
• d2tmkb_ appears in SCOPe 2.02
  
• d2tmkb_ appears in the current release, SCOPe 2.08