SCOPe 2.08: Domain d5i4vb1: 5i4v B:297-528

Lineage for d5i4vb1 (5i4v B:297-528)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d5i4vb1: 5i4v B:297-528 [319043]
   Other proteins in same PDB: d5i4vb2
   automated match to d4j5xc_
   complexed with 67s

Details for d5i4vb1

PDB Entry: 5i4v, 2.61 Å

PDB Description: discovery of novel, orally efficacious liver x receptor (lxr) beta agonists

PDB Compounds: (B:) Retinoic acid receptor RXR-beta,Nuclear receptor coactivator 2

SCOPe Domain Sequences for d5i4vb1:

Sequence, based on SEQRES records:

>d5i4vb1 a.123.1.1 (B:297-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eempvdrileaelaveqksdqgvegpggtggsgsspndpvtnicqaadkqlftlvewakr
iphfsslplddqvillragwnelliasfshrsidvrdgillatglhvhrnsahsagvgai
fdrvltelvskmrdmrmdktelgclraiilfnpdakglsnpsevevlrekvyasletyck
qkypeqqgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemlea

Sequence, based on observed residues (ATOM records):

>d5i4vb1 a.123.1.1 (B:297-528) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eempvdrileaelavepvtnicqaadkqlftlvewakriphfsslplddqvillragwne
lliasfshrsidvrdgillatglhvhrnsahsagvgaifdrvltelvskmrdmrmdktel
gclraiilfnpdakglsnpsevevlrekvyasletyckqkypeqqgrfaklllrlpalrs
iglkclehlfffklipidtflmemlea

Timeline for d5i4vb1:

• d5i4vb1 first appeared in SCOPe 2.06
  
• d5i4vb1 appears in SCOPe 2.07