SCOP 1.71: Domain d1vtk__: 1vtk -

Lineage for d1vtk__ (1vtk -)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (23 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (18 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidine kinase [52552] (3 species)
   contains insert all-alpha subdomain, res. 251-322

7. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (22 PDB entries)

8. Domain d1vtk__: 1vtk - [31882]
   complexed with adp, tmp

Details for d1vtk__

PDB Entry: 1vtk, 2.75 Å

PDB Description: thymidine kinase from herpes simplex virus type 1 in complex with adp and deoxythymidine-monophosphate

SCOP Domain Sequences for d1vtk__:

Sequence, based on SEQRES records:

>d1vtk__ c.37.1.1 (-) Thymidine kinase {Herpes simplex virus type 1, different strains}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremgean

Sequence, based on observed residues (ATOM records):

>d1vtk__ c.37.1.1 (-) Thymidine kinase {Herpes simplex virus type 1, different strains}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagspppaltlifdrhpiaa
llcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerld
lamlaairrvygllantvrylqcggswredwgqlsgprphigdtlftlfrapellapngd
lynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticd
lartfaremgean

Timeline for d1vtk__:

• d1vtk__ first appeared (with stable ids) in SCOP 1.55
  
• d1vtk__ appears in SCOP 1.69
  
• d1vtk__ is called d1vtka_ in SCOP 1.73
  
• d1vtk__ appears in the current release, SCOPe 2.08, called d1vtka_