Lineage for d1ki2b_ (1ki2 B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2109205Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 protein domains)
    parallel beta-sheet of 5 strands, order 23145
  6. 2109585Protein Thymidine kinase [52552] (4 species)
    contains insert all-alpha subdomain, res. 251-322
  7. 2109599Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (33 PDB entries)
    Uniprot P03176 46-375
  8. 2109637Domain d1ki2b_: 1ki2 B: [31871]
    protein/DNA complex; complexed with ga2, so4

Details for d1ki2b_

PDB Entry: 1ki2 (more details), 2.2 Å

PDB Description: crystal structure of thymidine kinase from herpes simplex virus type i complexed with ganciclovir
PDB Compounds: (B:) Thymidine kinase

SCOPe Domain Sequences for d1ki2b_:

Sequence, based on SEQRES records: (download)

>d1ki2b_ c.37.1.1 (B:) Thymidine kinase {Herpes simplex virus type 1, different strains [TaxId: 10298]}
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremgea

Sequence, based on observed residues (ATOM records): (download)

>d1ki2b_ c.37.1.1 (B:) Thymidine kinase {Herpes simplex virus type 1, different strains [TaxId: 10298]}
mptllrvyidgphgmgkttttqllvalgdivyvpepmtywrvlgasetianiyttqhrld
qgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhpiaa
llcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerld
lamlaairrvygllantvrylqcggswredwgqlsnagprphigdtlftlfrapellapn
gdlynvfawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipti
cdlartfaremgea

SCOPe Domain Coordinates for d1ki2b_:

Click to download the PDB-style file with coordinates for d1ki2b_.
(The format of our PDB-style files is described here.)

Timeline for d1ki2b_: