SCOPe 2.06: Domain d5acbd_: 5acb D:

Lineage for d5acbd_ (5acb D:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d5acbd_: 5acb D: [318677]
   Other proteins in same PDB: d5acba1, d5acba2, d5acbb1, d5acbb2
   automated match to d5efqc_
   complexed with 5i1

Details for d5acbd_

PDB Entry: 5acb, 2.7 Å

PDB Description: crystal structure of the human cdk12-cyclink complex

PDB Compounds: (D:) cyclin-dependent kinase 12

SCOPe Domain Sequences for d5acbd_:

Sequence, based on SEQRES records:

>d5acbd_ d.144.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dwgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireiki
lrqlihrsvvnmkeivtdkqdaldfkkdkgafylvfeymdhdlmgllesglvhfsedhik
sfmkqlmegleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnkvi
tlwyrppelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcp
avwpdviklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqs
dflkdvelskmappdlphwqdchelws

Sequence, based on observed residues (ATOM records):

>d5acbd_ d.144.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dwgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireiki
lrqlihrsvvnmkeivtdkqfkkdkgafylvfeymdhdlmgllesglvhfsedhiksfmk
qlmegleychkknflhrdikcsnillnnsgqikladfglarlynsrpytnkvitlwyrpp
elllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcpavwpdvi
klpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqsdflkdve
lskmappdlphwqdchelws

Timeline for d5acbd_:

• d5acbd_ appears in the current release, SCOPe 2.07