Lineage for d1ngsb2 (1ngs B:338-534)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2108258Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 2108259Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 2108389Family c.36.1.6: TK-like Pyr module [88735] (2 protein domains)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 2108404Protein Transketolase (TK), Pyr module [88736] (4 species)
  7. 2108405Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88737] (7 PDB entries)
  8. 2108417Domain d1ngsb2: 1ngs B:338-534 [31822]
    Other proteins in same PDB: d1ngsa1, d1ngsa3, d1ngsb1, d1ngsb3
    complexed with ca, e4p, tpp

Details for d1ngsb2

PDB Entry: 1ngs (more details), 2.4 Å

PDB Description: complex of transketolase with thiamin diphosphate, ca2+ and acceptor substrate erythrose-4-phosphate
PDB Compounds: (B:) transketolase

SCOPe Domain Sequences for d1ngsb2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1ngsb2 c.36.1.6 (B:338-534) Transketolase (TK), Pyr module {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}

SCOPe Domain Coordinates for d1ngsb2:

Click to download the PDB-style file with coordinates for d1ngsb2.
(The format of our PDB-style files is described here.)

Timeline for d1ngsb2: