SCOPe 2.06: Domain d5jaea_: 5jae A:

Lineage for d5jaea_ (5jae A:)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (1 family)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein Na(+):neurotransmitter symporter homologue LeuT [161072] (1 species)

7. Species Aquifex aeolicus [TaxId:63363] [161073] (38 PDB entries)
   Uniprot O67854 5-513

8. Domain d5jaea_: 5jae A: [318003]
   automated match to d4hmka_
   complexed with bog

Details for d5jaea_

PDB Entry: 5jae, 2.5 Å

PDB Description: leut in the outward-oriented, na+-free return state, p21 form at ph 6.5

PDB Compounds: (A:) Transporter

SCOPe Domain Sequences for d5jaea_:

Sequence, based on SEQRES records:

>d5jaea_ f.54.1.1 (A:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsil
irgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgv
wiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaav
affgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpm
iafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliif
fwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtv
witrfyiiglflfltflvflaerrrnhes

Sequence, based on observed residues (ATOM records):

>d5jaea_ f.54.1.1 (A:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpeppatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilir
giskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwi
aavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaf
fgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffagltssiaimqpmia
fledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffw
ifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtvwi
trfyiiglflfltflvflaerrrnhes

Timeline for d5jaea_:

• d5jaea_ is new in SCOPe 2.06-stable
  
• d5jaea_ appears in SCOPe 2.07
  
• d5jaea_ appears in the current release, SCOPe 2.08