SCOPe 2.08: Domain d5e4na_: 5e4n A:

Lineage for d5e4na_ (5e4n A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.8: Class-II DAHP synthetase [141840] (2 proteins)
   Pfam PF01474

6. Protein Probable DAHP synthetase AroG, phenylalanine-repressible [141841] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [141842] (11 PDB entries)
   Uniprot O53512 1-462

8. Domain d5e4na_: 5e4n A: [317934]
   automated match to d3kgfa_
   complexed with cl, dty, mn, so4

Details for d5e4na_

PDB Entry: 5e4n, 2.05 Å

PDB Description: 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis with d-tyrosine bound in the tyrosine and phenylalanine binding sites

PDB Compounds: (A:) 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase

SCOPe Domain Sequences for d5e4na_:

Sequence, based on SEQRES records:

>d5e4na_ c.1.10.8 (A:) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqvia
npvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghq
viwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvtec
lggaqdisetdlagryetacdprlntqqslelaflvaemlrd

Sequence, based on observed residues (ATOM records):

>d5e4na_ c.1.10.8 (A:) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
mnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppvtv
pseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygasmp
vvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasaam
nlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnlqt
aeiyashealvldyeramlrlsdgepqlfdlsahtvwigertrqidgahiafaqvianpv
gvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatghqviw
qcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvteclgg
aqdisetdlagryetacdprlntqqslelaflvaemlrd

Timeline for d5e4na_:

• d5e4na_ first appeared in SCOPe 2.06
  
• d5e4na_ appears in SCOPe 2.07