Lineage for d4zvvd2 (4zvv D:160-331)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2556795Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 2556796Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 2556797Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 2556804Protein Lactate dehydrogenase [56339] (20 species)
  7. 2556875Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [64445] (29 PDB entries)
  8. 2556925Domain d4zvvd2: 4zvv D:160-331 [317597]
    Other proteins in same PDB: d4zvva1, d4zvvb1, d4zvvc1, d4zvvd1
    automated match to d4jnka2
    complexed with gn0, nad, so4

Details for d4zvvd2

PDB Entry: 4zvv (more details), 2.2 Å

PDB Description: lactate dehydrogenase a in complex with a trisubstituted piperidine-2, 4-dione inhibitor gne-140
PDB Compounds: (D:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4zvvd2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4zvvd2 d.162.1.1 (D:160-331) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}
sgcnldsarfrylmgerlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgt
dkdkeqwkevhkqvvesayeviklkgytswaiglsvadlaesimknlrrvhpvstmikgl
ygikddvflsvpcilgqngisdlvkvtltseeearlkksadtlwgiqkelqf

SCOPe Domain Coordinates for d4zvvd2:

Click to download the PDB-style file with coordinates for d4zvvd2.
(The format of our PDB-style files is described here.)

Timeline for d4zvvd2: