Lineage for d4zvva1 (4zvv A:1-159)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2102557Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2102558Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2105555Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)
  6. 2105594Protein Lactate dehydrogenase [51859] (18 species)
  7. 2105660Species Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (16 PDB entries)
  8. 2105707Domain d4zvva1: 4zvv A:1-159 [317575]
    Other proteins in same PDB: d4zvva2, d4zvvb2, d4zvvc2, d4zvvd2
    automated match to d4jnka1
    complexed with gn0, nad, so4

Details for d4zvva1

PDB Entry: 4zvv (more details), 2.2 Å

PDB Description: lactate dehydrogenase a in complex with a trisubstituted piperidine-2, 4-dione inhibitor gne-140
PDB Compounds: (A:) L-lactate dehydrogenase A chain

SCOPe Domain Sequences for d4zvva1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4zvva1 c.2.1.5 (A:1-159) Lactate dehydrogenase {Human (Homo sapiens), muscle isoform (M chain) [TaxId: 9606]}

SCOPe Domain Coordinates for d4zvva1:

Click to download the PDB-style file with coordinates for d4zvva1.
(The format of our PDB-style files is described here.)

Timeline for d4zvva1: