SCOPe 2.07: Domain d1qpbb1: 1qpb B:182-360

Lineage for d1qpbb1 (1qpb B:182-360)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 protein domains)
   N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold

6. Protein Pyruvate decarboxylase [52478] (3 species)
   rudiment domain with a variant fold, lacks FAD-binding

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52480] (2 PDB entries)

8. Domain d1qpbb1: 1qpb B:182-360 [31740]
   Other proteins in same PDB: d1qpba2, d1qpba3, d1qpbb2, d1qpbb3
   complexed with mg, pym, tpp

Details for d1qpbb1

PDB Entry: 1qpb, 2.4 Å

PDB Description: pyruvate decarboyxlase from yeast (form b) complexed with pyruvamide

PDB Compounds: (B:) pyruvate decarboxylase (form b)

SCOPe Domain Sequences for d1qpbb1:

Sequence; same for both SEQRES and ATOM records:

>d1qpbb1 c.31.1.3 (B:182-360) Pyruvate decarboxylase {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
qtpidmslkpndaesekevidtilvlikdaknpviladaccsrhdvkaetkklidltqfp
afvtpmgkgsideqhpryggvyvgtlskpevkeavesadlilsvgallsdfntgsfsysy
ktknivefhsdhmkirnatfpgvqmkfvlqklltaiadaakgykpvavpartpanaavp

Timeline for d1qpbb1:

• d1qpbb1 first appeared (with stable ids) in SCOP 1.55
  
• d1qpbb1 appears in SCOPe 2.06