Lineage for d2hgsa1 (2hgs A:202-303)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2106806Fold c.30: PreATP-grasp domain [52439] (1 superfamily)
    3 layers: a/b/a; parallel or mixed beta-sheet of 4 to 6 strands
    possible rudiment form of Rossmann-fold domain
  4. 2106807Superfamily c.30.1: PreATP-grasp domain [52440] (10 families) (S)
    precedes the ATP-grasp domain common to all superfamily members, can contain a substrate-binding function
  5. 2107013Family c.30.1.4: Eukaryotic glutathione synthetase, substrate-binding domain [52460] (1 protein)
    circularly permuted version of prokaryotic enzyme
    automatically mapped to Pfam PF03199
  6. 2107014Protein Eukaryotic glutathione synthetase, substrate-binding domain [52461] (2 species)
  7. 2107020Species Human (Homo sapiens) [TaxId:9606] [52462] (1 PDB entry)
  8. 2107021Domain d2hgsa1: 2hgs A:202-303 [31722]
    Other proteins in same PDB: d2hgsa4
    complexed with adp, gsh, mg, so4

Details for d2hgsa1

PDB Entry: 2hgs (more details), 2.1 Å

PDB Description: human glutathione synthetase
PDB Compounds: (A:) protein (glutathione synthetase)

SCOPe Domain Sequences for d2hgsa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hgsa1 c.30.1.4 (A:202-303) Eukaryotic glutathione synthetase, substrate-binding domain {Human (Homo sapiens) [TaxId: 9606]}
pnalvlliaqekernifdqraienellarnihvirrtfedisekgsldqdrrlfvdgqei
avvyfrdgymprqyslqnwearlllershaakcpdiatqlag

SCOPe Domain Coordinates for d2hgsa1:

Click to download the PDB-style file with coordinates for d2hgsa1.
(The format of our PDB-style files is described here.)

Timeline for d2hgsa1:

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Domains from same chain:
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d2hgsa4