SCOPe 2.07: Domain d4zt4b1: 4zt4 B:-1-606

Lineage for d4zt4b1 (4zt4 B:-1-606)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.0: automated matches [191377] (1 protein)
   not a true family

6. Protein automated matches [190459] (59 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:999953] [226467] (29 PDB entries)

8. Domain d4zt4b1: 4zt4 B:-1-606 [317169]
   Other proteins in same PDB: d4zt4a2, d4zt4b2, d4zt4b3
   automated match to d4eg8b1
   protein/RNA complex; complexed with 4ro, dms, gol, met, so4

Details for d4zt4b1

PDB Entry: 4zt4, 2.3 Å

PDB Description: trypanosoma brucei methionyl-trna synthetase in complex with inhibitorn-(3,5-dichlorobenzyl)-2,2-difluoro-n'-(1h-imidazo[4,5- b]pyridin-2-yl)propane-1,3-diamine (chem 1708)

PDB Compounds: (B:) Methionyl-tRNA synthetase

SCOPe Domain Sequences for d4zt4b1:

Sequence, based on SEQRES records:

>d4zt4b1 c.26.1.0 (B:-1-606) automated matches {Trypanosoma brucei [TaxId: 999953]}
smkvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkva
eaakqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdi
ylgryegwysisdesfltpqnitdgvdkdgnpckvslesghvvtwvseenymfrlsafre
rllewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvw
ldaltnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsa
glplpkkivahgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdys
dknmiarlngel

Sequence, based on observed residues (ATOM records):

>d4zt4b1 c.26.1.0 (B:-1-606) automated matches {Trypanosoma brucei [TaxId: 999953]}
smkvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkva
eaakqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdi
ylgryegwysisdesfltpqnitvslesghvvtwvseenymfrlsafrerllewyhanpg
civpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwldaltnyltgs
rlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsaglplpkkivah
gwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdysdknmiarlnge
l

Timeline for d4zt4b1:

• d4zt4b1 first appeared in SCOPe 2.06
  
• d4zt4b1 appears in the current release, SCOPe 2.08