SCOPe 2.08: Domain d4zt6b1: 4zt6 B:237-606

Lineage for d4zt6b1 (4zt6 B:237-606)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.0: automated matches [191377] (1 protein)
   not a true family

6. Protein automated matches [190459] (61 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:999953] [226467] (29 PDB entries)

8. Domain d4zt6b1: 4zt6 B:237-606 [317159]
   Other proteins in same PDB: d4zt6a2, d4zt6b2, d4zt6b3
   automated match to d4eg8b1
   protein/RNA complex; complexed with 4rd, dms, met

Details for d4zt6b1

PDB Entry: 4zt6, 2.25 Å

PDB Description: trypanosoma brucei methionyl-trna synthetase in complex with inhibitor n-[(4r)-6,8-dichloro-3,4-dihydro-2h-chromen-4-yl]-n'-(5-fluoro-1h- imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (chem 1709)

PDB Compounds: (B:) Methionyl-tRNA synthetase

SCOPe Domain Sequences for d4zt6b1:

Sequence, based on SEQRES records:

>d4zt6b1 c.26.1.0 (B:237-606) automated matches {Trypanosoma brucei [TaxId: 999953]}
kvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkvaea
akqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdiyl
gryegwysisdesfltpqnitdgvdkdgnpckvslesghvvtwvseenymfrlsafrerl
lewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwld
altnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsagl
plpkkivahgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdysdk
nmiarlngel

Sequence, based on observed residues (ATOM records):

>d4zt6b1 c.26.1.0 (B:237-606) automated matches {Trypanosoma brucei [TaxId: 999953]}
kvekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkvaea
akqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdiyl
gryegwysisdesfltpqnitdgkvslesghvvtwvseenymfrlsafrerllewyhanp
gcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwldaltnyltg
srlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsaglplpkkiva
hgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdysdknmiarlng
el

Timeline for d4zt6b1:

• d4zt6b1 first appeared in SCOPe 2.06
  
• d4zt6b1 appears in SCOPe 2.07