SCOPe 2.08: Domain d4zt5b2: 4zt5 B:607-767

Lineage for d4zt5b2 (4zt5 B:607-767)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.27: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1 superfamily)
   core: 4 helices; bundle; one loop crosses over one side of the bundle

4. Superfamily a.27.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (2 families)

5. Family a.27.1.0: automated matches [227164] (1 protein)
   not a true family

6. Protein automated matches [226872] (13 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:999953] [226468] (29 PDB entries)

8. Domain d4zt5b2: 4zt5 B:607-767 [317117]
   Other proteins in same PDB: d4zt5a1, d4zt5b1, d4zt5b3
   automated match to d4eg8b2
   protein/RNA complex; complexed with 4rn, dms, gol, met, so4

Details for d4zt5b2

PDB Entry: 4zt5, 2.35 Å

PDB Description: trypanosoma brucei methionyl-trna synthetase in complex with inhibitor (2s)-n-(3,5-dichlorobenzyl)-n'-(1h-imidazo[4,5-b]pyridin-2-yl)-2- methylpropane-1,3-diamine (chem 1655)

PDB Compounds: (B:) Methionyl-tRNA synthetase

SCOPe Domain Sequences for d4zt5b2:

Sequence; same for both SEQRES and ATOM records:

>d4zt5b2 a.27.1.0 (B:607-767) automated matches {Trypanosoma brucei [TaxId: 999953]}
adtlgnlvmrctsakinvngewpspaayteedesliqlikdlpgtadhyylipdiqkaii
avfdvlrainayvtdmapwklvktdperlrtvlyitlegvrvttlllspilprksvvifd
mlgvpevhrkgienfefgavppgtrlgpavegevlfskrst

Timeline for d4zt5b2:

• d4zt5b2 first appeared in SCOPe 2.06
  
• d4zt5b2 appears in SCOPe 2.07