SCOPe 2.08: Domain d4zt4a2: 4zt4 A:607-767

Lineage for d4zt4a2 (4zt4 A:607-767)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.27: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322] (1 superfamily)
   core: 4 helices; bundle; one loop crosses over one side of the bundle

4. Superfamily a.27.1: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323] (2 families)

5. Family a.27.1.0: automated matches [227164] (1 protein)
   not a true family

6. Protein automated matches [226872] (13 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:999953] [226468] (29 PDB entries)

8. Domain d4zt4a2: 4zt4 A:607-767 [317109]
   Other proteins in same PDB: d4zt4a1, d4zt4b1, d4zt4b3
   automated match to d4eg8b2
   protein/RNA complex; complexed with 4ro, dms, gol, met, so4

Details for d4zt4a2

PDB Entry: 4zt4, 2.3 Å

PDB Description: trypanosoma brucei methionyl-trna synthetase in complex with inhibitorn-(3,5-dichlorobenzyl)-2,2-difluoro-n'-(1h-imidazo[4,5- b]pyridin-2-yl)propane-1,3-diamine (chem 1708)

PDB Compounds: (A:) Methionyl-tRNA synthetase

SCOPe Domain Sequences for d4zt4a2:

Sequence; same for both SEQRES and ATOM records:

>d4zt4a2 a.27.1.0 (A:607-767) automated matches {Trypanosoma brucei [TaxId: 999953]}
adtlgnlvmrctsakinvngewpspaayteedesliqlikdlpgtadhyylipdiqkaii
avfdvlrainayvtdmapwklvktdperlrtvlyitlegvrvttlllspilprksvvifd
mlgvpevhrkgienfefgavppgtrlgpavegevlfskrst

Timeline for d4zt4a2:

• d4zt4a2 first appeared in SCOPe 2.06
  
• d4zt4a2 appears in SCOPe 2.07