SCOPe 2.08: Domain d5hjpd1: 5hjp D:219-461

Lineage for d5hjpd1 (5hjp D:219-461)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Oxysterols receptor LXR-beta [89149] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89150] (21 PDB entries)
   Uniprot P55055 219-461

8. Domain d5hjpd1: 5hjp D:219-461 [316755]
   Other proteins in same PDB: d5hjpa1, d5hjpa2, d5hjpb2, d5hjpc1, d5hjpc2, d5hjpd2
   automated match to d1p8da_
   complexed with 668, peg

Details for d5hjpd1

PDB Entry: 5hjp, 2.6 Å

PDB Description: identification of lxrbeta selective agonists for the treatment of alzheimer's disease

PDB Compounds: (D:) oxysterols receptor lxr-beta

SCOPe Domain Sequences for d5hjpd1:

Sequence, based on SEQRES records:

>d5hjpd1 a.123.1.1 (D:219-461) Oxysterols receptor LXR-beta {Human (Homo sapiens) [TaxId: 9606]}
qltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpasgsasqqrfahftelaiis
vqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskd
dfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqp
yveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwd
vhe

Sequence, based on observed residues (ATOM records):

>d5hjpd1 a.123.1.1 (D:219-461) Oxysterols receptor LXR-beta {Human (Homo sapiens) [TaxId: 9606]}
qltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwpsasqqrfahftelaiisvqeivdfa
kqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglq
vefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsy
trikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdvhe

Timeline for d5hjpd1:

• d5hjpd1 first appeared in SCOPe 2.06
  
• d5hjpd1 appears in SCOPe 2.07