Lineage for d5l3aa_ (5l3a A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984752Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2984753Protein automated matches [190417] (37 species)
    not a true protein
  7. 2984910Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)
  8. 2985780Domain d5l3aa_: 5l3a A: [316325]
    automated match to d4e4ma_
    complexed with 6dp

Details for d5l3aa_

PDB Entry: 5l3a (more details), 1.98 Å

PDB Description: fragment-based discovery of 6-arylindazole jak inhibitors
PDB Compounds: (A:) Tyrosine-protein kinase JAK2

SCOPe Domain Sequences for d5l3aa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5l3aa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptqfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereie
ilkslqhdnivkykgvcysagrrnlklimeylpygslrdylqkhkeridhikllqytsqi
ckgmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeffkvkepgespifw
yapeslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhlie
llknngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnm

SCOPe Domain Coordinates for d5l3aa_:

Click to download the PDB-style file with coordinates for d5l3aa_.
(The format of our PDB-style files is described here.)

Timeline for d5l3aa_: