SCOP 1.65: Domain d1tpt_2: 1tpt 71-335

Lineage for d1tpt_2 (1tpt 71-335)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.27: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52417] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 32145; Rossmann-like

4. Superfamily c.27.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52418] (1 family)

5. Family c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52419] (3 proteins)

6. Protein Thymidine phosphorylase [52420] (1 species)

7. Species Escherichia coli [TaxId:562] [52421] (4 PDB entries)

8. Domain d1tpt_2: 1tpt 71-335 [31627]
   Other proteins in same PDB: d1tpt_1, d1tpt_3
   complexed with so4, tdr

Details for d1tpt_2

PDB Entry: 1tpt, 2.8 Å

PDB Description: three-dimensional structure of thymidine phosphorylase from escherichia coli at 2.8 angstroms resolution

SCOP Domain Sequences for d1tpt_2:

Sequence; same for both SEQRES and ATOM records:

>d1tpt_2 c.27.1.1 (71-335) Thymidine phosphorylase {Escherichia coli}
dwkslhlngpivdkhstggvgdvtslmlgpmvaacggyipmisgrglghtggtldklesi
pgfdifpddnrfreiikdvgvaiigqtsslapadkrfyatrditatvdsiplitasilak
klaegldalvmdvkvgsgafmptyelsealaeaivgvangagvrttalltdmnqvlassa
gnavevreavqfltgeyrnprlfdvtmalcvemlisgklakddaearaklqavldngkaa
evfgrmvaaqkgptdfvenyakylp

Timeline for d1tpt_2:

• d1tpt_2 first appeared (with stable ids) in SCOP 1.55
  
• d1tpt_2 appears in SCOP 1.63
  
• d1tpt_2 appears in SCOP 1.67
  
• d1tpt_2 appears in the current release, SCOPe 2.08, called d1tpta2