SCOPe 2.08: Domain d5g2na2: 5g2n A:525-725

Lineage for d5g2na2 (5g2n A:525-725)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (28 families)

5. Family a.118.1.0: automated matches [191340] (1 protein)
   not a true family

6. Protein automated matches [190220] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189070] (63 PDB entries)

8. Domain d5g2na2: 5g2n A:525-725 [316194]
   Other proteins in same PDB: d5g2na1, d5g2na3, d5g2na4
   automated match to d1e8ya1
   complexed with 6e2, so4

Details for d5g2na2

PDB Entry: 5g2n, 2.68 Å

PDB Description: x-ray structure of pi3kinase gamma in complex with copanlisib

PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d5g2na2:

Sequence, based on SEQRES records:

>d5g2na2 a.118.1.0 (A:525-725) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslk
hpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraia
vqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseia
qsrhyqqrfavileaylrgcg

Sequence, based on observed residues (ATOM records):

>d5g2na2 a.118.1.0 (A:525-725) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hpiaaempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgq
qeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyl
lqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileay
lrgcg

Timeline for d5g2na2:

• d5g2na2 first appeared in SCOPe 2.06
  
• d5g2na2 appears in SCOPe 2.07