SCOPe 2.06: Domain d5fvua_: 5fvu A:

Lineage for d5fvua_ (5fvu A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187302] (35 PDB entries)

8. Domain d5fvua_: 5fvu A: [316101]
   automated match to d4ucha_
   complexed with edo, h4b, hem, w64, zn; mutant

Details for d5fvua_

PDB Entry: 5fvu, 2.22 Å

PDB Description: structure of human nnos r354a g357d mutant heme domain in complex with 4-methyl-6-(2-(5-(4-methylpiperazin-1-yl) pyridin-3-yl)ethyl)pyridin-2-amine

PDB Compounds: (A:) Nitric oxide synthase, brain

SCOPe Domain Sequences for d5fvua_:

Sequence, based on SEQRES records:

>d5fvua_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cprflkvknwetevvltdtlhlkstletgcteyicmgsimhpsqharrpedvatkdqlfp
lakefidqyyssikrfgskahmerleevnkeidttstyqlkdteliygakhawrnasrcv
griqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwn
sqliryagykqpdgstlgdpanvqfteiciqqgwkpprgrfdvlplllqangndpelfqi
ppelvlevpirhpkfewfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvr
dycdnsrynileevakkmnldmrktsslwkdqalveiniavlysfqsdkvtivdhhsate
sfikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw
k

Sequence, based on observed residues (ATOM records):

>d5fvua_ d.174.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cprflkvknwetevvltdtlhlkstletgcteyicmgsimhpdvatkdqlfplakefidq
yyssikrfgskahmerleevnkeidttstyqlkdteliygakhawrnasrcvgriqwskl
qvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliryag
ykqpdgstlgdpanvqfteiciqqgwkpprgrfdvlplllqangndpelfqippelvlev
pirhpkfewfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdnsry
nileevakkmnldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhmen
eyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwk

Timeline for d5fvua_:

• d5fvua_ is new in SCOPe 2.06-stable
  
• d5fvua_ appears in SCOPe 2.07
  
• d5fvua_ appears in the current release, SCOPe 2.08