SCOPe 2.06: Domain d5hpsa_: 5hps A:

Lineage for d5hpsa_ (5hps A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (2 families)
   automatically mapped to Pfam PF00632

5. Family d.148.1.0: automated matches [227207] (1 protein)
   not a true family

6. Protein automated matches [226939] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225255] (16 PDB entries)

8. Domain d5hpsa_: 5hps A: [315509]
   Other proteins in same PDB: d5hpsb_
   automated match to d4y07a_

Details for d5hpsa_

PDB Entry: 5hps, 2.05 Å

PDB Description: system-wide modulation of hect e3 ligases with selective ubiquitin variant probes: wwp1 and ubv p1.1

PDB Compounds: (A:) wwp1 hect

SCOPe Domain Sequences for d5hpsa_:

Sequence, based on SEQRES records:

>d5hpsa_ d.148.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iayergfrwklahfrylcqsnalpshvkinvsrqtlfedsfqqimalkpydlrrrlyvif
rgeegldygglarewffllshevlnpmyclfeyagknnyclqinpastinpdhlsyfcfi
grfiamalfhgkfidtgfslpfykrmlskkltikdlesidtefynsliwirdnnieecgl
emyfsvdmeilgkvtshdlklggsnilvteenkdeyiglmtewrfsrgvqeqtkafldgf
nevvplqwlqyfdekelevmlcgmqevdladwqrntvyrhytrnskqiiwfwqfvketdn
evrmrllqfvtgtcrlplggfaelmgsngpqkfciekvgkdtwlprshtcfnrldlppyk
syeqlkekllfaieete

Sequence, based on observed residues (ATOM records):

>d5hpsa_ d.148.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iayergfrwklahfrylcqsnalpshvkinvsrqtlfedsfqqimalkpydlrrrlyvif
rgeeygglarewffllshevlnpmyclfeyagknnyclqinpastinpdhlsyfcfigrf
iamalfhgkfidtgfslpfykrmlskkltikdlesidtefynsliwirdnnieecglemy
fsvdmeilgkvtshdlklggsnilvteenkdeyiglmtewrfsrgvqeqtkafldgfnev
vplqwlqyfdekelevmlcgmqevdladwqrntvyrhytrnskqiiwfwqfvketdnevr
mrllqfvtgtcrlplggfaelmgsngpqkfciekvgkdtwlprshtcfnrldlppyksye
qlkekllfaieete

Timeline for d5hpsa_:

• d5hpsa_ is new in SCOPe 2.06-stable
  
• d5hpsa_ appears in SCOPe 2.07
  
• d5hpsa_ appears in the current release, SCOPe 2.08